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mifepristone will boost the level or influence of modafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.Xiao et al (2004) used article mortem examination in the brains of MPTP treated mice. They found that modafinil reduced striatal GABA, amplified the amounts of reduced glutathione in MPTP ruined neurons, and reduce